Novel coumarin-thiazolyl ester derivatives as potential DNA gyrase Inhibitors: Design, synthesis, and antibacterial activity
Hao Liu, Dong-Guo Xia, Zhiwen Chu, Rui Hu, Xiang Cheng, Xianhai Lv
Topics & Concepts
DNA gyraseChemistryCoumarinEscherichia coliAntibacterial activityDNAMinimum inhibitory concentrationBiochemistryIn vitroStereochemistryDocking (animal)Listeria monocytogenesBacteriaOrganic chemistryBiologyGeneNursingGeneticsMedicineCancer therapeutics and mechanismsSynthesis and Biological EvaluationSynthesis and biological activity