Age-Specific Resurgence in Invasive Pneumococcal Disease Incidence in the COVID-19 Pandemic Era and Its Association With Respiratory Virus and Pneumococcal Carriage Dynamics: A Time-Series Analysis
Alexis Rybak, Zein Assad, Corinne Lévy, Stéphane Bonarcorsi, Stéphane Béchet, A. Werner, Alain Wollner, Zaba Valtuille, Florentia Kaguelidou, François Angoulvant, Robert Cohen, Emmanuelle Varon, Naïm Ouldali
Abstract
Using multiple national surveillance systems, we found an increase in the incidence of invasive pneumococcal disease during after the relaxation of non-pharmaceutical interventions against COVID-19, which strongly varied by age. Age groups with higher incidence of respiratory syncytial virus and influenza also experienced higher increase in invasive pneumococcal disease incidence, with no change in pneumococcal carriage.
Topics & Concepts
Incidence (geometry)CarriageMedicinePandemicPneumococcal diseasePneumococcal infectionsRespiratory systemStreptococcus pneumoniaeCoronavirus disease 2019 (COVID-19)DiseaseImmunologyVirologyPediatricsInfectious disease (medical specialty)Internal medicineBiologyPathologyMicrobiologyAntibioticsPhysicsOpticsPneumonia and Respiratory InfectionsRespiratory viral infections researchEmergency and Acute Care Studies