Allicin alleviated acrylamide-induced NLRP3 inflammasome activation via oxidative stress and endoplasmic reticulum stress in Kupffer cells and SD rats liver
Bo Nan, Chaoyue Yang, Lu Li, Haiqing Ye, Haiyang Yan, Minghua Wang, Yuan Yuan
Topics & Concepts
AllicinUnfolded protein responseEndoplasmic reticulumChemistryInflammasomeOxidative stressChemical chaperoneReactive oxygen speciesp38 mitogen-activated protein kinasesCYP2E1BiochemistryHepatoprotectionSignal transductionCell biologyPharmacologyMAPK/ERK pathwayGlutathioneBiologyIn vitroReceptorMicrosomeEnzymePotato Plant ResearchGarlic and Onion StudiesChemotherapy-induced organ toxicity mitigation