Modulation of cyclic topology toward enhanced drug delivery, from linear and tadpole-like to dumbbell-shaped copolymers
Guiying Kang, Yuping Liu, Lingxia Li, Lu Sun, Wei Ma, Chao Meng, Liwei Ma, Guohua Zheng, Cong Chang, Hua Wei
Abstract
In this study, an efficient strategy for the synthesis of dumbbell-shaped amphiphilic copolymers with cyclic moieties as the two bells was developed and the enhanced performance of dumbbell-shaped copolymers for controlled drug release because of the simultaneous introduction of two macrocycles was disclosed.
Topics & Concepts
DumbbellTadpole (physics)Modulation (music)CopolymerTopology (electrical circuits)Materials scienceDrug deliveryPhysicsNanotechnologyBiologyPolymerMathematicsComposite materialCombinatoricsQuantum mechanicsPhysiologyAcousticsAdvanced Polymer Synthesis and CharacterizationSupramolecular Chemistry and ComplexesNanoparticle-Based Drug Delivery