Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature‐Based Undivided Perspective
Muhammad Torequl Islam, Cristina Quispe, Jesús Herrera‐Bravo, Chandan Kumar Sarkar, Rohit Sharma, Neha Garg, Larry Ibarra Fredes, Miquel Martorell, Mohammed M. Alshehri, Javad Sharifi‐Rad, Sevgi Durna Daştan, Daniela Călina, Radi Alsafi, Saad Alghamdi, Gaber El‐Saber Batiha, Natália Martins
Abstract
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical environments, mostly found in urban and semiurban areas. Unfortunately, there is no particular therapeutic approach, but prevention, adequate consciousness, detection at earlier stage of viral infection, and appropriate medical care can lower the fatality rates. This review offers a comprehensive view of production, transmission, pathogenesis, and control measures of the dengue virus and its vectors.