An active metabolite of the anti-COVID-19 drug molnupiravir impairs mouse preimplantation embryos at clinically relevant concentrations
Yusuke Marikawa, Vernadeth B. Alarcón
Topics & Concepts
BlastocystMetaboliteToxicityPharmacologyEmbryoActive metaboliteBiologyDrugMechanism of actionToxicantNucleosideTherapeutic indexChemistryIn vitroBiochemistryCell biologyEmbryogenesisOrganic chemistryCOVID-19 Impact on ReproductionVirus-based gene therapy researchRNA Interference and Gene Delivery