Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients.
Bailin Jiang, Hannah Wei
Abstract
OBJECTIVE: Hypoxia is one of the primary causes that leads to multiple organ injuries and death in COVID-19 patients. Aggressive oxygen therapy for the treatment of hypoxia is important in saving these patients. We have summarized the mechanisms, efficacy, and side effects of various oxygen therapy techniques and their status or the potential to treat hypoxia in COVID-19 patients. The benefit to risk ratio of each oxygen therapy technique and strategy to use them in COVID-19 patients are discussed. High flow nasal cannula oxygen (HFNO) should be considered a better choice as an early stage oxygen therapy. Supraglottic jet oxygenation and ventilation (SJOV) is a promising alternative for HFNO with potential benefits.
Topics & Concepts
Oxygen therapyHypoxia (environmental)Nasal cannulaCoronavirus disease 2019 (COVID-19)MedicineOxygenationOxygen2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Oxygen deliveryCannulaIntensive care medicineAnesthesiaDiseaseSurgeryInternal medicineInfectious disease (medical specialty)ChemistryPathologyOutbreakOrganic chemistryRespiratory Support and MechanismsCardiac Arrest and ResuscitationThermal Regulation in Medicine