Transcriptomics and metabolomics analyses provide insights into the difference in toxicity of benzo[a]pyrene and 6-chlorobenzo[a]pyrene to human hepatic cells
Yun Luo, Baoqin Zhang, Ningbo Geng, Shuai Sun, Xiaoyao Song, Jiping Chen, Haijun Zhang
Topics & Concepts
Benzo(a)pyrenePyreneMetabolismToxicityChemistryTranscriptomeMetabolomicsBiochemistryMetabolic pathwayOxidative stressCarcinogenStereochemistryGeneGene expressionChromatographyOrganic chemistryToxic Organic Pollutants ImpactMetabolomics and Mass Spectrometry StudiesPharmacogenetics and Drug Metabolism