Lipotoxicity-induced circGlis3 impairs beta cell function and is transmitted by exosomes to promote islet endothelial cell dysfunction
Li Xiong, Li Chen, Liting Wu, Weiman He, Dubo Chen, Zishan Peng, Jin Li, Xiaonan Zhu, Lei Su, Yanbing Li, Yingying Gong, Haipeng Xiao
Topics & Concepts
LipotoxicityMicrovesiclesBeta cellCell biologyExosomeIsletBiologyInternal medicineEndocrinologyDiabetes mellitusMedicinemicroRNAInsulin resistanceBiochemistryGeneCircular RNAs in diseasesEndoplasmic Reticulum Stress and DiseaseCancer-related molecular mechanisms research