Commensal Bacteria Impact a Protozoan’s Integration into the Murine Gut Microbiota in a Dietary Nutrient-Dependent Manner
Yanxia Wei, Jing Gao, Yanbo Kou, Liyuan Meng, Xingping Zheng, Liang Ming, Hongxiang Sun, Zhuanzhuan Liu, Yugang Wang
Abstract
Like commensal bacteria, commensal protozoa are an integral part of the vertebrate intestinal microbiome. How protozoa integrate into a commensal bacterium-enriched ecosystem remains poorly studied. Here, using the murine commensal Tritrichomonas musculis as a proof of concept, we studied potential factors involved in shaping the intestinal protozoal-bacterial community. Understanding the rules by which microbes form a multispecies community is crucial to prevent or correct microbial community dysfunctions in order to promote the host’s health or to treat diseases.
Topics & Concepts
CommensalismBiologyMicrobiomeProtozoaBacteriaMicrobiologyHost (biology)Protozoan infectionEcologyGeneticsGut microbiota and healthVibrio bacteria research studiesProbiotics and Fermented Foods