Role of The PD-1 and PD-L1 Axis in COVID-19
Srinivasa Reddy Bonam, Haitao Hu, Jagadeesh Bayry
Abstract
Tweetable abstract Severe COVID-19 patients display dysregulated expression of checkpoint molecules PD-1 and its ligand PD-L1, suggesting that these checkpoint molecules could be considered as prognostic markers and therapeutic targets in severe cases of COVID-19.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PD-L12019-20 coronavirus outbreakLigand (biochemistry)VirologyMedicineBiologyImmunologyGeneticsReceptorInternal medicineImmune systemImmunotherapyInfectious disease (medical specialty)DiseaseOutbreakCOVID-19 Clinical Research StudiesCancer Immunotherapy and BiomarkersPhagocytosis and Immune Regulation