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Ochratoxin A: Overview of Prevention, Removal, and Detoxification Methods

Lijuan Ding, Meihua Han, Xiangtao Wang, Yifei Guo

2023Toxins91 citationsDOIOpen Access PDF

Abstract

, among which ochratoxin A (OTA) is the most toxic molecule. OTA is widely found in food and agricultural products. Due to its severe nephrotoxicity, immunotoxicity, neurotoxicity, and teratogenic mutagenesis, it is essential to develop effective, economical, and environmentally friendly methods for OTA decontamination and detoxification. This review mainly summarizes the application of technology in OTA prevention, removal, and detoxification from physical, chemical, and biological aspects, depending on the properties of OTA, and describes the advantages and disadvantages of each method from an objective perspective. Overall, biological methods have the greatest potential to degrade OTA. This review provides some ideas for searching for new strains and degrading enzymes.

Topics & Concepts

Detoxification (alternative medicine)Ochratoxin AOchratoxinsBiotechnologyHuman decontaminationMycotoxinAflatoxinOchratoxinPatulinToxicologyBiologyBiochemical engineeringMedicineEngineeringPathologyAlternative medicineMycotoxins in Agriculture and FoodAnalytical chemistry methods developmentListeria monocytogenes in Food Safety
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