Homology-directed repair protects the replicating genome from metabolic assaults
Kumar Somyajit, Julian Spies, Fabian Coscia, Ufuk Kirik, Maj‐Britt Rask, Ji‐Hoon Lee, Kai J. Neelsen, Andreas Mund, Lars Juhl Jensen, Tanya T. Paull, Matthias Mann, Jiri Lukas
Topics & Concepts
BiologyDNA damageRibonucleotide reductaseCell biologyDNA repairDNA replicationGenome instabilityReplisomeDNADNA re-replicationEukaryotic DNA replicationDNA polymeraseGeneticsGeneProtein subunitDNA Repair MechanismsEpigenetics and DNA MethylationCRISPR and Genetic Engineering