External stimuli-responsive nanoparticles for spatially and temporally controlled delivery of CRISPR–Cas genome editors
Ruosen Xie, Yuyuan Wang, Shaoqin Gong
Abstract
In this review, we summarize the state-of-the-art non-viral vectors that exploit external stimuli ( i.e. , light, magnetic field, and ultrasound) for spatially and temporally controlled genome editing and their in vitro and in vivo applications.
Topics & Concepts
CRISPRGenome editingCas9GenomeComputational biologyComputer scienceIn vivoExploitBiologyGeneticsGeneComputer securityCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques