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The impact of near infrared fluorescence imaging on parathyroid function after total thyroidectomy

Yoo Seok Kim, Ozgun Erten, Bora Kahramangil, Hüsnü Aydın, Mustafa Dönmez, Eren Berber

2020Journal of Surgical Oncology55 citationsDOI

Abstract

BACKGROUND: Compared with conventional thyroidectomy, hypocalcemia rate was reported to be lower after total thyroidectomy (TT) utilizing near infrared fluorescence imaging (NIFI). The aim of this study is to evaluate the impact of NIFI on postoperative parathyroid function after TT. METHODS: and t test. RESULTS: Average number of parathyroid glands identified intraoperatively was similar between two groups. However, rate of incidental parathyroidectomy was higher in conventional (14%) versus NIFI group (6%) (P = .039), despite similar (4% vs 6%, respectively) autotransplantation rates (P = .562). Incidences of transient (6.5% vs 5.0%) and permanent (0.5% vs 0%) hypocalcemia were not statistically different between conventional and NIFI groups (P = NS). CONCLUSION: The use of NIFI during thyroidectomy may decrease the rate of incidental parathyroidectomy by increasing the ability of the surgeon to recognize parathyroid glands with fluorescent contrast distinction. Nevertheless, in contrary to recent reports in literature, postoperative hypocalcemia rate was not altered compared with conventional technique, suggesting that preservation of parathyroid vasculature, rather than an augmented ability to detect the glands, may dominantly affect postoperative function.

Topics & Concepts

MedicineParathyroidectomyThyroidectomyHypoparathyroidismAutotransplantationSurgeryUrologyParathyroid hormoneInternal medicineThyroidCalciumTransplantationThyroid and Parathyroid SurgeryParathyroid Disorders and TreatmentsThyroid Cancer Diagnosis and Treatment