RXRγ attenuates cerebral ischemia–reperfusion induced ferroptosis in neurons in mice through transcriptionally promoting the expression of GPX4
Lei Yang, Baoshun Du, Shitao Zhang, Maode Wang
Topics & Concepts
Downregulation and upregulationGPX4Gene knockdownRetinoid X receptorTranscription factorBiologyChemistryCell biologyPharmacologyEndocrinologyGlutathione peroxidaseOxidative stressBiochemistryNuclear receptorApoptosisCatalaseGeneFerroptosis and cancer prognosisMicroRNA in disease regulationCancer-related molecular mechanisms research