Mechanisms of aortic carboxypeptidase-like protein secretion and identification of an intracellularly retained variant associated with Ehlers–Danlos syndrome
Neya Vishwanath, William J. Monis, Gwendolyn A. Hoffmann, Bhavana Ramachandran, Vincent DiGiacomo, Joyce Wong, Michael L. Smith, Matthew D. Layne
Abstract
-linked glycosylation of ACLP for its secretion and contribute to our understanding of ACLP-dependent disease pathologies.
Topics & Concepts
Endoplasmic reticulumGlycosylationExtracellular matrixSecretionUnfolded protein responseThrombospondinsCell biologyBiologyBiochemistryChemistryMolecular biologyThrombospondinMatrix metalloproteinaseMetalloproteinaseConnective tissue disorders researchProtease and Inhibitor MechanismsGalectins and Cancer Biology