Menadione: a platform and a target to valuable compounds synthesis
Acácio S. de Souza, Ruan C. B. Ribeiro, Dora C. S. Costa, Fernanda P. Pauli, David R Pinho, Matheus G de Moraes, Fernando de Carvalho da Silva, Luana da Silva Magalhães Forezi, Vı́tor F. Ferreira
Abstract
Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoquinone belonging to the vitamin K group. This compound can be synthesized by different methods and it has a broad range of biological and synthetic applications, which will be highlighted in this review.
Topics & Concepts
MenadioneChemistryNaphthoquinoneCombinatorial chemistryDerivative (finance)BiochemistryOrganic chemistryOxidative stressEconomicsFinancial economicsBioactive Compounds and Antitumor AgentsOrganic Chemistry Cycloaddition ReactionsMorinda citrifolia extract uses