Dihydroartemisinin increased the abundance of Akkermansia muciniphila by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD-1 immunotherapy
Zhiqin Zhang, Xinli Shi, Jingmin Ji, Yinglin Guo, Qing Peng, Liyuan Hao, Yu Xue, Yi-Wei Liu, Caige Li, Junlan Lu, Kun Yu
Topics & Concepts
Akkermansia muciniphilaHepatocellular carcinomaCancer researchImmunotherapyDihydroartemisininMedicineInternal medicineBiologyPharmacologyImmunologyCancerGut floraArtemisininMalariaPlasmodium falciparumHippo pathway signaling and YAP/TAZAutophagy in Disease and TherapyPhagocytosis and Immune Regulation