Transdermal on-demand drug delivery based on an iontophoretic hollow microneedle array system
Usanee Detamornrat, Marc Parrilla, Juan Domínguez‐Robles, Qonita Kurnia Anjani, Eneko Larrañeta, Karolien De Wael, Ryan F. Donnelly
Abstract
in the skin and receptor compartment) was analysed to untangle the different delivery profiles according to the types of molecule. Finally, the integration of the anode and cathode into an iontophoretic hollow microneedle array system (IHMAS) offers the full miniaturisation of the concept. Overall, the IHMAS device provides a versatile wearable technology for transdermal on-demand drug delivery that can improve the administration of personalised doses, and potentially enhance precision medicine.
Topics & Concepts
IontophoresisTransdermalDelivery systemEx vivoDrug deliveryIn vivoPharmacologyBiomedical engineeringDrugOn demandMedicineNanotechnologyMaterials scienceComputer scienceBiologyBiotechnologyRadiologyMultimediaAdvancements in Transdermal Drug DeliveryLipid Membrane Structure and BehaviorDermatology and Skin Diseases