Lipid accumulation-induced hepatocyte senescence regulates the activation of hepatic stellate cells through the Nrf2-antioxidant response element pathway
Huiyuan Yu, Xin Jiang, Fangyuan Dong, Fan Zhang, Xueying Ji, Mengjuan Xue, Fan Yang, Jie Chen, Xiaona Hu, Zhijun Bao
Topics & Concepts
SenescenceHepatocyteHepatic stellate cellBiologyDownregulation and upregulationFatty liverOxidative stressFibrosisSteatohepatitisSteatosisCell biologyHepatic fibrosisEndocrinologyInternal medicineCancer researchBiochemistryIn vitroMedicineDiseaseGeneLiver Disease Diagnosis and TreatmentGenomics, phytochemicals, and oxidative stressLiver Disease and Transplantation