Synthesis, characterization and <i>in vitro</i> anticancer activity of thiabendazole-derived 1,2,3-triazole derivatives
Khadija El Bourakadi, Mohamed El Mehdi Mekhzoum, Charles Saby, Hamid Morjani, Hind Chakchak, Nawal Merghoub, Abou el kacem Qaiss, Rachid Bouhfid
Abstract
Thiabendazolium salts with 1,2,3-triazole motifs were synthesized and characterized; they exhibit good cytotoxic activity.
Topics & Concepts
ChemistryIn vitroCytotoxic T cell1,2,4-TriazoleTriazoleStereochemistryCombinatorial chemistry1,2,3-TriazoleOrganic chemistryBiochemistryClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Biological Evaluation