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Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury

Rui-Rui Luo, Jing Yang, Yanlin Sun, Biying Zhou, Sixuan Zhou, Guo‐Xing Zhang, Aixiang Yang

2024Naunyn-Schmiedeberg s Archives of Pharmacology15 citationsDOI

Topics & Concepts

LipopolysaccharideDexmedetomidineKEAP1PharmacologyOxidative stressLipid peroxidationLipid AAcute kidney injuryKidneyAgonistChemistryCreatinineEndocrinologyInternal medicineReceptorMedicineBiochemistryTranscription factorGeneSedationFerroptosis and cancer prognosisEicosanoids and Hypertension PharmacologyGlutathione Transferases and Polymorphisms
Dexmedetomidine attenuates ferroptosis by Keap1-Nrf2/HO-1 pathway in LPS-induced acute kidney injury | Litcius