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The need for improved methodology in protein corona analysis

Morteza Mahmoudi

2022Nature Communications84 citationsDOIOpen Access PDF

Abstract

The protein corona is a key component controlling biological activity, that develops on foreign materials when introduced to biological environments. This comment discusses the risk of errors from poor methodology that can lead to misinterpretation and poor outcomes. The protein corona is a key component controlling biological activity, that develops on foreign materials when introduced to biological environments. This comment discusses the risk of errors from poor methodology that can lead to misinterpretation and poor corona analysis which can impact diagnostic and clinical applications.

Topics & Concepts

Component (thermodynamics)Key (lock)Corona (planetary geology)Computer scienceRisk analysis (engineering)Biochemical engineeringNanotechnologyBiologyMaterials scienceMedicineEngineeringPhysicsComputer securityThermodynamicsAstrobiologyVenusBlood properties and coagulationIron Metabolism and DisordersAdvanced Proteomics Techniques and Applications
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