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Hip Arthroscopic Microfracture Augmented With Platelet‐Rich Plasma‐Infused Micronized Cartilage Allograft Significantly Improves Functional Outcomes

T. David Luo, Edward C. Beck, Amy P. Trammell, Michael W. Koulopoulos, Carl Edge, Alejandro Marquez‐Lara, Ian Al’Khafaji, Michael S. Schallmo, Allston J. Stubbs

2022Arthroscopy The Journal of Arthroscopic and Related Surgery12 citationsDOI

Abstract

PURPOSE: To evaluate functional outcomes and survivorship in patients at 1 year after undergoing arthroscopic microfracture augmented with hyaline allograft for symptomatic chondral defects of the hip. METHODS: Consecutive patients with and without prior hip procedures presenting with Outerbridge grade IV chondral lesion of the acetabulum or femoral head were prospectively followed. Patients underwent hip microfracture augmented with hyaline allograft suspended in autologous platelet-rich plasma between October 2016 and April 2018. Extent of cartilage degeneration was quantified using the chondromalacia severity index (CMI). Patient functional scores, including Tegner, Hip Outcome Score-Activities of Daily Living (HOS-ADL), Sport-Specific Subscale (HOS-SSS), modified Harris Hip Score (mHHS), and Nonarthritic Hip Score (NAHS) were collected preoperatively and at minimum 1-year postoperatively. Minimal clinically important difference (MCID) was analyzed. Statistical significance was established at P < .05. Pearson's coefficient analysis was performed to identify preoperative variables correlated with clinical outcomes. RESULTS: , respectively. Comparison of baseline and postoperative score averages demonstrated significant improvements in Tegner scores (3.7 ± 2.9 vs 5.1 ± 2.6; P = .003), HOS-ADL (63.3 ± 16.4 vs 89.1 ± 14.5; P < .001), HOS-SSS (40.8 ± 20.4 vs 79.5 ± 21.6; P < .001), mHHS (61.5 ± 16.2 vs 87.0 ± 17.7; P < .001), and NAHS (56.6 ± 14.9 vs 78.7 ± 18.3; P < .001). The percentage of patients who achieved MCID for HOS-ADL, HOS-SSS, mHHS, and NAHS were 89.8%, 83.0%, 75.6%, and 81.6%, respectively. Overall, 91.8% of patients met the threshold for achieving MCID in at least one outcome score. Of the 57 patients, 5 (8.8%) failed clinically, with 1 (1.8%) undergoing revision surgery and 4 (6.9%) undergoing conversion to total hip arthroplasty. There was a direct correlation between preoperative alpha angle and postoperative HOS-ADL. Femoral chondral lesion size and CMI inversely correlated with postoperative HOS-ADL. CONCLUSIONS: Treatment of hip chondral defects with microfracture and hyaline allograft augmentation demonstrated excellent survivorship and significantly improved patient report outcomes at 1 year. LEVEL OF EVIDENCE: IV, retrospective case series.

Topics & Concepts

MedicineHarris Hip ScoreSurgeryAcetabulumHip arthroscopySSS*Minimal clinically important differenceHip surgeryBody mass indexOsteoarthritisArthroscopyArthroplastyInternal medicineRandomized controlled trialPathologyAlternative medicineHip disorders and treatmentsBone and Joint DiseasesOrthopaedic implants and arthroplasty
Hip Arthroscopic Microfracture Augmented With Platelet‐Rich Plasma‐Infused Micronized Cartilage Allograft Significantly Improves Functional Outcomes | Litcius