Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria
Puneet Labana, Mark H. Dornan, Matthew A. Lafrenière, Tomasz L. Czarny, Eric D. Brown, John Paul Pezacki, Christopher N. Boddy
Topics & Concepts
FtsZProteasesBacteriaBacillus subtilisCell divisionMicrobiologyBiologyMode of actionAntibioticsBacterial cell structureMechanism of actionMreBCell biologyCellBiochemistryIn vitroEnzymeGeneticsCytoskeletonAntibiotic Resistance in BacteriaRNA and protein synthesis mechanismsBacterial Genetics and Biotechnology