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Stereoselective Iridium-N,P-Catalyzed Double Hydrogenation of Conjugated Enones to Saturated Alcohols

Bram B. C. Peters, Jia Zheng, Suppachai Krajangsri, Pher G. Andersson

2022Journal of the American Chemical Society20 citationsDOIOpen Access PDF

Abstract

, 99/1 d.r.) resulting in a highly stereoselective reduction of enones.

Topics & Concepts

ChemistryIridiumStereocenterStereoselectivityBenzamideCatalysisAsymmetric hydrogenationReactivity (psychology)Conjugated systemYield (engineering)Noyori asymmetric hydrogenationOrganic chemistryMedicinal chemistryCombinatorial chemistryEnantioselective synthesisPolymerMedicinePathologyMetallurgyAlternative medicineMaterials scienceAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and CatalysisAdvanced Synthetic Organic Chemistry