Digital microfluidics with distance-based detection – a new approach for nucleic acid diagnostics
Man Ho, N. Sathishkumar, Alexandros A. Sklavounos, Jianxian Sun, Minqing Ivy Yang, Kevin P. Nichols, Aaron R. Wheeler
Abstract
copies per mL), all in an automated system that does not require detection apparatus for analysis. We propose that the combination of DMF with distance-based detection may be a powerful one for implementing a variety of POC NAATs or for other applications in the future.
Topics & Concepts
MicrofluidicsDigital microfluidicsNucleic acidNucleic acid detectionComputer scienceNanotechnologyEngineeringBiologyMaterials scienceElectrical engineeringGeneticsVoltageElectrowettingElectrowetting and Microfluidic TechnologiesBiosensors and Analytical DetectionMicrofluidic and Capillary Electrophoresis Applications