Development of depression in patients with oral cavity cancer: a systematic review
Mira Westphal Lansner, Kathrine Kronberg Jakobsen, Jakob Schmidt Jensen, Karl Erik Sandsten, Christian Grønhøj, Christian von Buchwald
Abstract
BACKGROUND: The incidence of oral cancer is approximately 300,000 patients annually. A cancer diagnosis and treatment affect both physical and mental issues. OBJECTIVES: The aim of this systematic review was to examine the development of depression in patients who have been treated for oral squamous cell carcinoma (OSCC). MATERIAL AND METHODS: PubMed and EMBASE were systematically searched for studies addressing depression among patients treated for OSCC and published within the past ten years. RESULTS: This systematic review showed that OSCC patients are at risk of developing depressive symptoms after treatment, though severity of symptoms varied. This knowledge could preferably be implemented in future follow-up regimes.