Feruloylated oligosaccharides ameliorate MPTP-induced neurotoxicity in mice by activating ERK/CREB/BDNF/TrkB signalling pathway
Yiru Ding, Meiyu Zhou, Ruoyin Zheng, Ruijia Ma, Jialin Deng, Wenzhi Hao, Lu Wang, Ji-chun Zhang, Chi-tang Ho, Junqing Huang
Topics & Concepts
MPTPNeuroprotectionNeuroinflammationPharmacologyPars compactaChemistrySubstantia nigraCREBDopamineMAPK/ERK pathwayTyrosine hydroxylaseNeurotoxicityTropomyosin receptor kinase BEndocrinologyInternal medicineNeurotrophic factorsSignal transductionBiochemistryMedicineToxicityTranscription factorDopaminergicInflammationReceptorGeneOrganic chemistryParkinson's Disease Mechanisms and TreatmentsNuclear Receptors and SignalingNeuroinflammation and Neurodegeneration Mechanisms