Characterization of an International High-Risk Escherichia coli ST410 Clone Coproducing NDM-5 and OXA-181 in a Food Market in China
Wan-Yun He, Luchao Lv, Wen-Xian Pu, Guolong Gao, Zilin Zhuang, Yaoyao Lu, Chao Zhuo, Jian–Hua Liu
Abstract
This is the first report of an Escherichia coli ST410 clone that coproduces NDM-5 and OXA-181 in China. The high similarity of the core genomes and plasmids between the ST410 isolates characterized in this study and human source isolates from foreign countries strongly suggests that this ST410 lineage is an international high-risk clone, highlighting the need for continuous global surveillance of ST410 clones.
Topics & Concepts
PlasmidBiologyGenBankEscherichia coliGenomeGeneticsPhylogenetic treeSingle-nucleotide polymorphismGenotypeMicrobiologyGeneAntibiotic Resistance in BacteriaPharmaceutical and Antibiotic Environmental ImpactsAntibiotics Pharmacokinetics and Efficacy