Systems redox biology in health and disease
Martin Feelisch, Miriam M. Cortese‐Krott, Jérôme Santolini, Stephen A. Wootton, Alan A. Jackson
Abstract
' allows each of these to be considered as distinct but complementary aspects of the same system, representative of roles at different levels of organization within a functional hierarchy. The versatile chemistry of sulfur - exemplified by hydrogen sulfide, glutathione and proteinous cysteine thiols - enriched by its interactions with reactive oxygen, nitrogen and sulfur species, would seem to sit at the heart of the 'Redox Code' and underpin the ability of complex organisms to cope with stress.
Topics & Concepts
OrganismStressorOxidative stressLiving systemsAdaptation (eye)HierarchyDiseasePerspective (graphical)Computational biologyBiologyComputer scienceEcologyMedicineBiochemistryNeurosciencePolitical scienceGeneticsArtificial intelligenceLawPathologySulfur Compounds in BiologyRedox biology and oxidative stressVitamin C and Antioxidants Research