Genomic analysis of paired IDHwt glioblastomas reveals recurrent alterations of MPDZ at relapse after radiotherapy and chemotherapy
Brice Chanez, Romain Appay, Arnaud Guillé, Arnaud Lagarde, Carole Colin, José Adélaı̈de, Emilie Denicolaï, Carine Jiguet‐Jiglaire, Céline Bequet, Thomas Graillon, Sébastien Boissonneau, Isabelle Nanni‐Metellus, Henry Dufour, Dominique Figarella‐Branger, Olivier Chinot, Émeline Tabouret
Topics & Concepts
BiologyOncologyRadiation therapyChemotherapyGeneCancer researchGliomaCancerComparative genomic hybridizationInternal medicineMedicineGeneticsGenomeHippo pathway signaling and YAP/TAZGlioma Diagnosis and TreatmentFOXO transcription factor regulation