EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives
Ahmed A.E. Mourad, N. A. Farouk, Elsherbiny H. El‐Sayed, Ahmed R. E. Mahdy
Topics & Concepts
ErlotinibChemistryEGFR inhibitorsApoptosisCell cultureCell cycleDocking (animal)Cytotoxic T cellADMEA549 cellCell cycle checkpointSorafenibIn vitroPharmacologyCancer researchEpidermal growth factor receptorBiochemistryBiologyReceptorMedicineNursingHepatocellular carcinomaGeneticsSynthesis and biological activityAngiogenesis and VEGF in CancerSynthesis of Organic Compounds