Sequence-specific and multiplex detection of COVID-19 virus (SARS-CoV-2) using proofreading enzyme-mediated probe cleavage coupled with isothermal amplification
Sheng Ding, Gangyi Chen, Yinghua Wei, Juan Dong, Feng Du, Xin Cui, Xin Huang, Zhuo Tang
Topics & Concepts
Loop-mediated isothermal amplificationProofreadingMultiplexSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)Reverse Transcription Loop-mediated Isothermal AmplificationCoronavirusMolecular biologyBiologyChemistryComputational biologyRNAReverse transcriptaseDNAMedicineGeneBioinformaticsBiochemistryPolymeraseDiseasePathologyInfectious disease (medical specialty)Biosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 detection and testing