Experimental and Clinical Studies of Mechanisms of the Antiaging Effects of Chemical Compounds in Astragalus membranaceus (Review)
М. А. Berezutsky, Н. А. Дурнова, I. A. Vlasova
Abstract
Astragalus membranaceus (webbed astragalus) for more than two millennia has been used in traditional Chinese medicine as a means of slowing down the aging process and increasing longevity. The article analyzes the data of experimental and clinical studies of recent years, identifying possible mechanisms of the anti-aging effects of the plant. It is noted that the extract or various groups of chemical compounds of this plant activate telomerase, inhibit the processes of replicative senescence, have antioxidant activity, have a neuroprotective effect, affect age-related macular degeneration, skin photoaging and alopecia.
Topics & Concepts
AstragalusPhotoagingTelomeraseTraditional medicineSenescenceTelomereAntioxidantMedicineNeuroprotectionPharmacologyBiologyTraditional Chinese medicineBiochemistryInternal medicineDermatologyPathologyAlternative medicineGeneDNATraditional Chinese Medicine AnalysisNephrotoxicity and Medicinal PlantsPhytochemical and Pharmacological Studies