Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice
Meilyn Sylvestre, Shixian Lv, Lucy F. Yang, Nicholas Luera, David J. Peeler, Bing‐Mae Chen, Steve R. Roffler, Suzie H. Pun
Topics & Concepts
MelittinPeptideChemistryPEG ratioPharmacologyAntibodyAmino acidBiochemistryMedicineImmunologyFinanceEconomicsDrug-Induced Adverse ReactionsCell Adhesion Molecules ResearchHeparin-Induced Thrombocytopenia and Thrombosis