Synthesis, molecular modelling study of the methaqualone analogues as anti-convulsant agent with improved cognition activity and minimized neurotoxicity
Iqrar Ahmad, Sazedur Rahman Akand, Matin Shaikh, Rahul Pawara, S Manjula, Harun Patel
Topics & Concepts
MethaqualoneChemistryConvulsantPharmacologyNeurotoxicityAcetylcholinesteraseED50Docking (animal)ReceptorToxicityStereochemistryEnzymeBiochemistryChromatographyOrganic chemistryNursingMedicineComputational Drug Discovery MethodsMulticomponent Synthesis of HeterocyclesSynthesis and pharmacology of benzodiazepine derivatives