Litcius/Paper detail

A unique CD4⁺ T cell subset expressing granzyme K is regulated by transcription factor EOMES and important for T cell-mediated intestinal inflammation

Tian Xie, Yizhou Du, Qihan Wang, Hao Zhang, Kun Wei, Xinxin Chi, Xue Bai, Yujie Fu, Zhilin Peng, Yicheng Zhu, Qiuyan Lan, Chen Dong

2026Nature Immunology5 citationsDOI

Topics & Concepts

T cellTranscription factorBiologyCell biologyInflammationCytotoxic T cellGranzyme ACd4 t cellGranzyme BGranzymeImmunologyInterleukin 21Molecular biologyChemistryRegulatory T cellImmune systemT-cell receptorTranscription (linguistics)Interleukin 3Cancer researchIntestinal mucosaImmune Cell Function and InteractionWhipple's Disease and InterleukinsReproductive System and Pregnancy