MnO2 nanoparticles trigger hepatic lipotoxicity and mitophagy via mtROS-dependent Hsf1Ser326 phosphorylation
Tao Zhao, Hua Zheng, Jiejie Xu, Kostas Pantopoulos, Yi-Chuang Xu, Lu‐lu Liu, Xi-Jun Lei, Yannis Kotzamanis, Zhi Luo
Topics & Concepts
LipotoxicityMitophagyOxidative phosphorylationCell biologyMitochondrial ROSMitochondrionLipogenesisChemistryOxidative stressBiochemistryBiologyLipid metabolismEndocrinologyAutophagyApoptosisInsulinInsulin resistanceTrace Elements in HealthHeavy Metal Exposure and ToxicityAutophagy in Disease and Therapy