UPLC-MS/MS method for the determination of Lenvatinib in rat plasma and its application to drug-drug interaction studies
Yanjun Cui, Ying Li, Liju Fan, Jing An, Xiaonan Wang, Ran Fu, Zhanjun Dong
Topics & Concepts
ChemistryChromatographyLenvatinibFormic acidPharmacokineticsCmaxAnalyteMass spectrometryLiquid chromatography–mass spectrometryExtraction (chemistry)High-performance liquid chromatographyEthyl acetateHepatocellular carcinomaPharmacologySorafenibBiologyMedicineCancer researchHepatocellular Carcinoma Treatment and PrognosisPharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms