Integrative analysis of metabolomic, genomic, and imaging-based phenotypes identify very-low-density lipoprotein as a potential risk factor for lumbar Modic changes
Yiming Li, Jaro Karppinen, Kathryn S.E. Cheah, Danny Chan, Pak C. Sham, Dino Samartzis
Topics & Concepts
Mendelian randomizationMetabolomicsMedicineGenome-wide association studySingle-nucleotide polymorphismMetaboliteModic changesLipoproteinMetabolomeInternal medicineSNPBioinformaticsGeneticsBiologyGenotypePathologyCholesterolLow back painGeneGenetic variantsAlternative medicineMetabolomics and Mass Spectrometry StudiesSpine and Intervertebral Disc PathologyMedical Imaging and Analysis