POSTN promotes nucleus pulposus cell senescence and extracellular matrix metabolism via activing Wnt/β-catenin and NF-κB signal pathway in intervertebral disc degeneration
Daxue Zhu, Shi‐Jie Chen, Pan Sheng, Zhaoheng Wang, Yanhu Li, Xuewen Kang
Topics & Concepts
Extracellular matrixWnt signaling pathwayCell biologyIntervertebral discNucleusCellular senescenceDegeneration (medical)SenescenceCateninSignal transductionExtracellularChemistryBiologyAnatomyPathologyMedicineBiochemistryGenePhenotypeSpine and Intervertebral Disc PathologyCervical and Thoracic MyelopathyCardiac Fibrosis and Remodeling