The Mitragyna speciosa (kratom) alkaloid mitragynine: Analysis of adrenergic α2 receptor activity in vitro and in vivo

Samuel Obeng, Morgan L. Crowley, Marco Mottinelli, Francisco León, Julio D. Zuarth Gonzalez, Yiming Chen, Lea R. Gamez-Jimenez, Luis Fernando Restrepo, Nicholas P. Ho, Avi Patel, Joelma Martins Rocha, Manuel Alvarez, Amsha Thadisetti, Chai R Park, Victoria L.C. Pallares, Megan J Milner, Clinton E. Canal, Aidan J. Hampson, Christopher R. McCurdy, Lance Richard McMahon, Jenny L. Wilkerson, Takato Hiranita