Plasma exosomes confer hypoxic pulmonary hypertension by transferring LOX-1 cargo to trigger phenotypic switching of pulmonary artery smooth muscle cells
Ning Huang, Di Wang, Tiantian Zhu, Xiao-Yue Ge, Hong Liu, Mao-Zhong Yao, Yanzi Guo, Jun Peng, Qing Wang, Zheng Zhang, Chang-Ping Hu
Topics & Concepts
MicrovesiclesPhenotypeCell biologyKLF4Pulmonary hypertensionPhenotypic switchingExosomeCancer researchChemistryBiologyMedicineInternal medicinemicroRNABiochemistryTranscription factorSOX2GeneExtracellular vesicles in diseasePulmonary Hypertension Research and TreatmentsCardiovascular Disease and Adiposity