The effect of metformin in EML4-ALK+ lung cancer alone and in combination with crizotinib in cell and rodent models
Abigail R. Bland, Nensi Shrestha, Rebekah L. Bower, Rhonda J. Rosengren, John C. Ashton
Topics & Concepts
CrizotinibMetforminLung cancerMedicineAnaplastic lymphoma kinasePharmacologyCancerIn vivoCancer researchInternal medicineBiologyInsulinBiotechnologyMalignant pleural effusionMetabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancerCancer-related Molecular Pathways