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Follicular Thyroid Adenoma Showing Avid Uptake on 68Ga-DOTA-FAPI-04 PET/CT

Lei Ou, Junhao Wu, Ji Wu, Chunru Mou, Chunyin Zhang

2021Clinical Nuclear Medicine14 citationsDOI

Abstract

ABSTRACT: We describe the case of a 48-year-old man suspected to have recurrent colon carcinoma who underwent 68Ga-DOTA-FAPI-04 PET/CT, revealing the presence of an incidentaloma with intense FAPI uptake in the left thyroid lobe. Based on PET/CT findings, malignancy was suspected. Biopsy confirmed the diagnosis of follicular thyroid adenoma with fibrosis and calcification. This case emphasizes the need to increase awareness of this benign lesion in the differential diagnosis of incidental thyroid nodules with high FAPI activity.

Topics & Concepts

MedicineThyroidMalignancyAdenomaBiopsyRadiologyFollicular phaseIncidentalomaPET-CTCalcificationDifferential diagnosisPathologyNuclear medicinePositron emission tomographyInternal medicinePeptidase Inhibition and AnalysisProtease and Inhibitor MechanismsCardiac Structural Anomalies and Repair