Enhancing PPARγ by HDAC inhibition reduces foam cell formation and atherosclerosis in ApoE deficient mice
Qi Gao, Wei Ai, Fang Chen, Xingren Chen, Wenwen Ding, Zhiquan Ding, Zhiwei Wu, Ronghui Du, Wangsen Cao
Topics & Concepts
Foam cellPeroxisome proliferator-activated receptorCell biologyNuclear receptorInflammationTrichostatin AABCA1ChemistryHistone deacetylaseTranscription factorCancer researchReceptorBiologyCholesterolHistoneBiochemistryImmunologyLipoproteinTransporterGenePeroxisome Proliferator-Activated ReceptorsNuclear Receptors and SignalingHistone Deacetylase Inhibitors Research