Factors associated with physical activity and exercise participation in people with multiple sclerosis: a qualitative systematic review
Chung Tak Chan, Krishna Kishore Garikipati
Abstract
Background Multiple Sclerosis (MS) is an incurable neuroinflammatory disease of the central nervous system that affects more than 2.2 million people globally. Although evidence shows the benefits of physical activity and exercise, participation in exercise in people with Multiple Sclerosis (pwMS) has been poor. A synthesis of qualitative research is required to better understand the factors associated with physical activity and exercise participation in pwMS.Objectives To synthesise findings from qualitative studies exploring factors associated with physical activity and exercise participation in people with MS.Methodology Qualitative systematic review using the Inductive Thematic Synthesis approach.Data sources CINAHL, Embase, MEDLINE, PsycINFO, and Scopus databases were systematically searched with further searches of reference lists and OpenGrey.Study eligibility criteria Qualitative studies or mixed-method studies with relevant qualitative content that explored the factors related to physical activity and exercise participation in people with MS.Study synthesis and appraisal Thematic Synthesis and Critical Appraisal Skills Programme (CASP) qualitative studies checklist.Results Thirty-nine studies met the inclusion criteria. Three analytical themes were generated from 11 descriptive themes outlining the factors associated with physical activity and exercise participation in people with MS.Conclusion Physical activity and exercise participation in people with MS is influenced by internal and external factors. PwMS adopt a range of strategies to sustain physical activity and exercise participation. Healthcare professionals could play a role in the physical activity and exercise participation of pwMS. Systematic Review Registration Number PROSPERO 2020:CRD42020214002.