A novel target and biomarker benzothiazolyl–naphthalimide probes for precise and selective detection of serum albumin and anticancer activity
Sudesh Rani, Saurabh Gupta, Vijay Luxami, Kamaldeep Paul
Abstract
N -Benzothiazolyl-1,8-naphthalimide based fluorescent probes were designed and synthesized for selective detection of human serum albumin (HSA) and bovine serum albumin (BSA) among various bioanalytes and further studied for their in vitro anti-proliferative activity against 60 human cancer cell lines.
Topics & Concepts
ChemistryBovine serum albuminHuman serum albuminIn vitroSerum albuminAlbuminBiomarkerFluorescenceBiochemistryPhysicsQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisAdvanced biosensing and bioanalysis techniquesMolecular Sensors and Ion Detection